Medicinal and Supramolecular Chemistry


Recognition-driven chemical biology

Epigenetic drug development

Post-translational modifications and the proteins that read them are cutting-edge drug targets.


Proteomics, Diagnostics and Novel Assays

We develop new research tools and analytical methods using recognition-based approaches.  (Antibodies – meh.)


High-throughput Supramolecular Chemistry

Parallel and high-throughput methods fuel fundamental discoveries about recognition in water and other complex fluids.


What’s New?

I was privileged to be a “fellow post-doc” of Jack’s—he was 80 at the time. Jack is so smart that his idle ruminations end up as highly cited papers.
One author + no original data + 100% brilliance = one-page paper in Science with 585 citations. READ IT!


The paper of the year on stereochemistry in @angew_chem from the “Professor’s Professor” Jack D. Dunitz FRS @ETH_DCHAB. A must read!

Facility manager: “I really need your group to clean all of that urine out of the freezer.”

Me: “but we’re using it!”

Finally saying goodbye to Aidan Pye - an undergrad who worked for 9.5(!) terms in the Hof lab, and who is now working in two different lab-teaching jobs. His excellent data features in a paper we just submitted last week. I'll also really really miss his group webpage headshot 🙁

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